Ultrasonographic Manifestations of Primary Hepatic Squamous Cell Carcinoma: A Case Report

Authors

  • Yuanqing Zhang Ultrasound Medical Center, Lanzhou University Second Hospital, PR China/Intelligence Ultrasound Center, Gansu Province Medical Engineering Research Center for Intelligence Ultrasound, PR China
  • Fang Nie Ultrasound Medical Center, Lanzhou University Second Hospital, PR China/Intelligence Ultrasound Center, Gansu Province Medical Engineering Research Center for Intelligence Ultrasound, PR China
  • Xiaorong Lv ¹Ultrasound Medical Center, Lanzhou University Second Hospital, PR China 2Ultrasound Center, Gansu Province Clinical Research Center for Ultrasound, PR China 3Intelligence Ultrasound Center, Gansu Province Medical Engineering Research Center for Intelligence Ultrasound, PR China
  • Guo Chen Guo Chen Ultrasound Medical Center, Lanzhou University Second Hospital, PR China/Intelligence Ultrasound Center, Gansu Province Medical Engineering Research Center for Intelligence Ultrasound, PR China
  • Rong Yang Ultrasound Medical Center, Lanzhou University Second Hospital, PR China/Intelligence Ultrasound Center, Gansu Province Medical Engineering Research Center for Intelligence Ultrasound, PR China
  • Ran Zheng Ultrasound Medical Center, Lanzhou University Second Hospital, PR China/Intelligence Ultrasound Center, Gansu Province Medical Engineering Research Center for Intelligence Ultrasound, PR China

DOI:

https://doi.org/10.3941/jrcr.5737

Abstract

Primary squamous cell carcinoma (SCC) of the liver is a rare type of cancer. Most patients are elderly men. This disease is difficult to diagnose, highly invasive, has a poor prognosis, and there are extremely few reports in domestic and foreign literatures, which are basically mainly case reports. This article reports a patient with primary squamous cell carcinoma of the liver and conducts a relevant literature review to improve clinicians' diagnosis of primary squamous cell carcinoma of the liver. In July 2024, our hospital admitted a 58-year-old female patient. Abdominal CT tomography considered cholangiocarcinoma of the liver; contrast-enhanced liver ultrasound suggested a malignant enhancement pattern, with a greater possibility of hepatocellular carcinoma. Later, after a puncture biopsy of the space-occupying lesion in the liver under ultrasound guidance, the analysis of the biopsy sample indicated squamous cell carcinoma. Therefore, the doctors in our hospital carried out imaging examinations to find the primary lesion. The results showed that the space-occupying lesion was primary squamous cell carcinoma of the liver, accompanied by metastasis to the hilar and abdominal lymph nodes. The patient was treated with Sintilimab + Bevacizumab and was discharged from the hospital after the condition stabilized.

Contrast-enhanced abdominal CT (A): Two-dimensional ultrasound (B): Contrast-enhanced ultrasound (C): The immunohistochemical results (D)

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Published

2025-08-31

Issue

Vol. 19 No. 8 (2025)

Section

General Radiology

License

Copyright (c) 2025 Journal of Radiology Case Reports

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