Gallstones with Multiple Biliary Hamartomas: A Case Report

Authors

  • Lianhai Zhao Department of Graduate, Shandong First Medical University & Shandong Academy of Medical Sciences, China
  • Aiyan Qiu Department of Hepatobiliary Surgery, The People’s Hospital of Binzhou Affiliated to Shandong First Medical University, China
  • Pingan Wang Department of Hepatobiliary Surgery, The People’s Hospital of Binzhou Affiliated to Shandong First Medical University, China
  • Dong Xue Department of Hepatobiliary Surgery, The People’s Hospital of Binzhou Affiliated to Shandong First Medical University, China

DOI:

https://doi.org/10.3941/jrcr.5693

Abstract

Multiple biliary hamartomas (MBH), also known as Von Meyenburg complexes (VMC), are rare congenital disorders characterized by multiple cystic biliary dilatations without significant gender or age predilection. Due to limited reported cases and a lack of standardized guidelines, the management of these patients remains a clinical challenge. However, MBH may mimic other hepatic tumors and carry a potential risk of malignant transformation. Clinicians should recognize this rare entity, understand its clinical and imaging features, and differentiate it from other cystic hepatic lesions to avoid unnecessary overtreatment. This article retrospectively analyzes the clinical data of one case of MBH and reviews relevant literature.

59-year-old male with Multiple biliary hamartomas (MBH) in liver. (2022) 2A: Multiple dark purple nodules of varying sizes (ranging from millimeters to centimeters) are scattered on the liver surface, with smooth surfaces. Their dark purple color suggests possible blood stasis or tissue changes, distinguishing them from normal liver tissue. 2B: Pathological images show multiple irregularly dilated biliary duct-like structures lined by uniform cuboidal epithelial cells, embedded in a dense, grayish-white, tough fibrous stroma. These findings are consistent with biliary hamartoma (magnification, ×100).

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Published

2025-04-30

Issue

Section

Gastrointestinal Radiology