A Rare Case Report --Mimicking Lymphoma 18F-FDG PET/ CT Findings of Blastic Plasmacytoid Dendritic Cell Tumor in a Young Female Patient

Authors

Hong Shao Mei Department of Radiology, Kiang Wu Hospital, Macao, China
Xiao Gang Department of Pathology, Kiang Wu Hospital, Macao, China
Ma LinFeng Department of Radiology, Kiang Wu Hospital, Macao, China

DOI:

Abstract

Blastic plasmacytoid dendritic cell neoplasm (BPDCN) is a rare hematologic malignancy originating from plasmacytoid dendritic cell precursors and is often misdiagnosed. Previous 18F-FDG PET/CT case reports have primarily involved middle-aged or elderly male patients. In this case, a 29-year-old female presented with misdiagnosed urticaria because of generalized rash and pruritus refractory to steroids. Back to hospital with recurrent enlarged and painful cervical lymph nodes after half a year. 18F-FDG PET/CT imaging revealed multiple small or slightly enlarged lymph nodes with FDG avidity throughout the body, as well as active bone marrow and active spleen, but no significant FDG uptake in the skin lesions. Imaging suggested a potential diagnosis of lymphoma. A cervical lymph node biopsy subsequently confirmed BPDCN.

Author Biography

Xiao Gang, Department of Pathology, Kiang Wu Hospital, Macao, China

A 29-year-old female with BPDCN presented with scattered flaky edematous erythema, irregular light red wheals, and small flaky brown spots on both lower limbs. Papules were scattered on both sides of the lower legs, with some surfaces covered by dark red scabs (Figure 1a). Large areas of pigmentation and brown spots were observed on the left forearm, along with several scattered dark red papules (Figure 1b).

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Published

2025-03-31

Issue

Vol. 19 No. 3 (2025)

Section

Nuclear Medicine / Molecular Imaging

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