The Role of MRI in Diagnosing Calcifying Pseudoneoplasms of the Neuraxis (CAPNON): A Rare Case Report of CAPNON with Corpus Callosum Agenesis and a Lipoma

Authors

  • Jeton Shatri Institute of Anatomy, Faculty of Medicine, University of Prishtina, Kosovo /Clinic of Radiology and Nuclear Medicine, University and Clinical Center of Kosovo https://orcid.org/0000-0002-0346-7867
  • Kreshnike Dedushi Hoti Clinic of Radiology and Nuclear Medicine, University and Clinical Center of Kosovo
  • Ardita Kafexholli Institute of Anatomy, Faculty of Medicine, University of Prishtina, Kosovo https://orcid.org/0000-0001-9107-685X
  • Jeton Kafexholli Clinic of Radiology and Nuclear Medicine, University and Clinical Center of Kosovo
  • Veton Kurti Clinic of Radiology and Nuclear Medicine, University and Clinical Center of Kosovo
  • Diar Kabashi Institute of Anatomy, Faculty of Medicine, University of Prishtina, Kosovo
  • Dijon Musliu Institute of Anatomy, Faculty of Medicine, University of Prishtina, Kosovo

DOI:

https://doi.org/10.3941/jrcr.5630

Abstract

Calcifying pseudoneoplasms of the neuraxis (CAPNON) are rare, benign lesions of the central nervous system, often misdiagnosed due to their nonspecific clinical and radiological presentations. We report a unique case of a 59-year-old male with persistent headaches, found to have a calcified mass in the left cerebral hemisphere associated with corpus callosum agenesis and an interhemispheric lipoma. MRI revealed a hypointense lesion with surrounding edema and compressive effects, complemented by CT findings of pronounced calcifications. The coexistence of CAPNON with corpus callosum agenesis and a lipoma is exceedingly rare, with few similar cases documented. This report underscores the critical role of MRI in diagnosing CAPNON and highlights its potential to mimic other central nervous system pathologies. Early recognition is essential to avoid misdiagnosis and guide appropriate management.

Coronal T2-weighted Magnetic Resonance Imaging (MRI) sequence;

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Published

2025-06-30

Issue

Vol. 19 No. 6 (2025)

Section

Neuroradiology

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