Pituitary Metastases from Thyroid Carcinoma: Case Series and Literature Review

Authors

  • Brett A. Fadrique Texas Tech University, Lubbock, USA
  • Levi Sanchez Ramirez Baylor College of Medicine, Houston, USA
  • Trevor Abts Creighton University School of Medicine, Omaha, USA
  • Salmaan Ahmed
  • J. Matthew Debnam Creighton University School of Medicine, Omaha, USA

DOI:

https://doi.org/10.3941/jrcr.5557

Abstract

Metastases to the pituitary gland are extremely rare. Most of the reported cases arise from breast and lung cancer, with metastases from thyroid cancer seldom reported. Thyroid cancer metastases to the pituitary gland may occur as the initial presentation of metastatic disease or part of widespread disease and may occur years after the primary thyroid cancer diagnosis. Herein, we present three cases of thyroid cancer that metastasized to the pituitary gland and review the literature to address its clinical and radiologic features, prognosis, treatment, and differential diagnosis.

 

A 61-year-old male with a pituitary metastasis from papillary thyroid carcinoma. (A,B) Coronal and sagittal T1 post-contrast MRIs show a homogenously enhancing metastasis involving the pituitary gland with narrowing of the mass at the diaphragma sella and thickening of the infundibulum (arrows). (C) Axial T1 post-contrast MRI shows metastases in the brain parenchyma (white arrows) and the pituitary infundibulum (black arrow).

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Published

2025-02-28

Issue

Section

General Radiology