Role of PET imaging in peritoneal involvement of subcutaneous panniculitis-like T-cell lymphoma


  • Darren Yak Leong Chan Singapore General Hospital
  • Nicholas Francis Grigoropoulos Singapore General Hospital
  • Amos Zhi En Tay Singapore General Hospital
  • Wanying Xie Singapore General Hospital



Subcutaneous panniculitis-like T-cell lymphoma, primary cutaneous lymphoma, peritoneum, anterior abdominal omentum, positron-emission tomography/computed tomography, PET/CT


Subcutaneous panniculitis-like T-cell lymphoma is a rare subtype of cutaneous T-cell lymphomas and represents less than 1% of non-Hodgkin's lymphomas. Currently, the diagnosis is based on clinical and histological findings although clinical features may be nonspecific. Often, it is localised to subcutaneous tissue without lymph node involvement. The literature is sparse but unusual presentations have been described to involve mesentery, breast and even eyelids. Fluorine-18 fluorodeoxyglucose positron-emission tomography/computed tomography has been reported to be useful in assessing disease activity, extent and treatment response in subcutaneous panniculitis-like T-cell lymphoma but we find that it can also be a diagnostic aid for atypical presentations. In our case report, we describe a patient who presented with a neck lump but did not have any other obvious cutaneous lesions. This was biopsied and had histological features in keeping with subcutaneous panniculitis-like T-cell lymphoma. Due to the atypical presentation, positron-emission tomography was crucial for detecting the extracutaneous and likely primary site of disease in the peritoneum, which hence guided the subsequent biopsy to this affected area and confirmed the diagnosis.

Author Biographies

Darren Yak Leong Chan, Singapore General Hospital

Resident, Department of Nuclear Medicine and Molecular Imaging

Nicholas Francis Grigoropoulos, Singapore General Hospital

Senior Consultant, Department of Haematology

Amos Zhi En Tay, Singapore General Hospital

Consultant, Department of Anatomical Pathology

Wanying Xie, Singapore General Hospital

Senior Consultant, Department of Nuclear Medicine and Molecular Imaging





Nuclear Medicine / Molecular Imaging