Neurocandidiasis: a case report and consideration of the causes of restricted diffusion

Authors

  • David J Lin
  • Ari Sacks
  • Jeanne Shen
  • Thomas Chung Hoon Lee

DOI:

https://doi.org/10.3941/jrcr.v7i5.1319

Keywords:

Neurocandidiasis, Central Nervous System Candida, Diffusion Weighted Imaging, Restricted Diffusion, Basal Ganglia

Abstract

Diffusion weighted magnetic resonance imaging has risen to the forefront of imaging for acute stroke. However, the differential diagnosis of restricted diffusion is wide and includes ischemia, metabolic derangements, infections, and highly-cellular masses. We present a case of central nervous system (CNS) candidiasis presenting radiographically as bilateral punctate areas of restricted magnetic resonance (MR) diffusion in the basal ganglia. This case illustrates the value of carefully considering the causes of restricted diffusion in the brain, notably to be broader than acute stroke and to include invasive fungal infections.

Author Biographies

David J Lin

Medical Student

Division of Health Sciences and Technology

Harvard Medical School

25 Shattuck Street

Boston, MA 02115

Department of Radiology

Brigham and Women's Hospital

75 Francis Street

Boston, MA 02115

Ari Sacks

Resident

Department of Radiology

Brigham and Women's Hospital

75 Francis Street

Boston, MA 02115

Jeanne Shen

Resident

Department of Pathology

Brigham and Women's Hospital

75 Francis Street

Boston, MA 02115

Thomas Chung Hoon Lee

Staff Neuroradiologist

Brigham and Women's Hospital

75 Francis Street

Boston, MA 02115

Journal of Radiology Case Reports May 2013 issue - Cover page: Sarcoidosis Manifesting as a Pseudotumorous Renal Mass by Goldsmith et al.

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Published

2013-05-11

Issue

Vol. 7 No. 5 (2013)

Section

Neuroradiology

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