Expansive Masses Arising From The Clivus: The Role Of FDG-PET/CT In The Metabolic Assessment Of Skeletal Lesions

Authors

  • Angelina Cistaro
  • Sabina Durando
  • Francesco Pazè
  • Andrea Limberti
  • Maurizio Cogoni
  • Carola Junemann
  • Isabella Morra
  • Maria Consuelo Valentini

DOI:

https://doi.org/10.3941/jrcr.v3i11.170

Keywords:

chordoma, plasmacytoma, clivus lesion, FDG-PET

Abstract

A patient with neurological symptoms underwent CT scan that showed a sellar and suprasellar mass with bone erosions, involving especially the clivus and the right petrous apex. The first diagnostic hypothesis was chordoma in relation to the mass position. The MRI showed a solid well-enhancing mass; moreover another circumscribed lesion, with similar signal pattern, was found in the left mandibular condyle. the signal and the presence of another lesion did not agree with diagnosis of chordoma. FDG-PET/CT study showed multiple pathological uptakes suggesting a metastatic disease. A trans-sphenoidal excisional biopsy was performed and the histopathological analysis showed a population of cells consistent with a plasmacell tumor, confirmed by the presence of a monoclonal gammopathy on blood analysis.
Our case suggests that FDG-PET/CT can modify the diagnostic and therapeutic procedures in  myeloma, by evaluating the bone marrow involvement.

Author Biography

Angelina Cistaro

Nuclear Medicine, Dr

Journal of Radiology Case Reports November 2009 issue cover page: Dural Based Mass: Malignant or Benign by Kurt Friedrich Scherer et al.

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Published

2009-08-23

Issue

Vol. 3 No. 11 (2009)

Section

Nuclear Medicine / Molecular Imaging

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