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Click Axial constrast-enhanced CT in the arterial phase (40 seconds after IV injection of 100 mL jomeprol 350 mg iodine/100mL, 120 kVp, 350 mAs, 5 mm slice thickness, 16-slice GE MDCT scanner). 65-y-old woman with fasciola hepatica. The CT images demonstrate a hypodense, lobulated lesion in the fourth liver segment; enhancement of the surrounding liver parenchyma, most probably because of mass effect.

Click Axial contrast-enhanced CT images in the equilibrium phase (70 seconds after IV injection of 100 mL jomeprol 350 mg iodine/100mL, 120 kVp, 350 mAs, 5 mm slice thickness, 16-slice GE MDCT scanner). 65-y-old woman with fasciola hepatica. The majority of the lesion enhances in equilibrium phase, becoming almost completely isodense to the surrounding liver parenchyma.

Click Axial unenhanced T1-weighted fat-saturated VIBE images (TE = 3 msec, TR = 6 msec, 5.0 mm slice thickness, 1.5 T Siemens MR scanner). 65-y-old woman with fasciola hepatica. A homogeneous, slightly hypo-intense solitary mass lesion can be seen in the 4th liver segment.

Click Axial T2-weighted fat-saturated images (6.5 mm slice thickness, 1.5 T Siemens MR scanner). 65-y-old woman with fasciola hepatica. A heterogeneous solitary liver lesion is seen in segment IV on the T2 image, consisting of multiple hypo-intense nodules, each demonstrating a bull's eye appearance.

Click Axial T1-weighted fat-saturated VIBE images (10 minutes after injection of 1.4 mL ferucarbotran, TE = 3 msec, TR = 6 msec, 5.0 mm slice thickness, 1.5 T Siemens MR scanner). 65-y-old woman with fasciola hepatica. Homogeneous, moderately hypo-intense solitary mass lesion with faintly enhancing rim.

Click Axial T2-weighted fat-saturated images (30 minutes after injection of 1.4 mL ferucarbotran, 6.0 mm slice thickness, 1.5 T Siemens MR scanner). 65-y-old woman with fasciola hepatica. The bulk of the lesion has become iso-intense to the rest of the liver, leaving a cluster of small, sharply delineated individual nodules, clearly discernible from the rest of the liver parenchyma, with preservation of their bull's eye configuration.

Click Sagittal T2-weighted fat-saturated images (30 minutes after injection of 1.4 mL ferucarbotran, 6.0 mm slice thickness, 1.5 T Siemens MR scanner). 65-y-old woman with fasciola hepatica. Same cluster of small individual nodules, with hyperintense periphery and central hyperintense dot.

Click Axial PET image (1 hour after IV injection of 300MBq fluorodeoxyglucose). 65-y-old woman with fasciola hepatica. The PET images show a small focal tracer uptake anteriorly in the right liver lobe.

Click Coronal PET maximum-intensity projection (MIP) images (1 hour after IV injection of 300MBq fluorodeoxyglucose). 65-y-old woman with fasciola hepatica. The MIP images show a small focal tracer uptake in the right liver lobe; the size and location of the lesion are consistent with the findings on CT.