The Teaching Point

Angiosarcoma of the liver is a rare mesenchymal tumor which can present in patients with underlying liver cirrhosis. In the current clinical scenario, it can present without the history of carcinogen exposure with which it is known to be associated. It has variable patterns of enhancement with a few salient distinctive imaging pointers which should be kept under consideration when reporting atypical hypervascular tumours in the liver.






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Angiosarcoma of the Liver: Imaging of a rare salient entity

Free full text article: Angiosarcoma of the Liver:  Imaging of a rare salient entity

Abstract
Hepatic angiosarcomas are rare mesenchymal tumors with few case series and reports describing their imaging findings in the last two decades. The computed tomography and magnetic resonance imaging findings are variable and may appear like hemangioma at one end of the spectrum and hepatoma at the other end. The use of hepatocyte specific contrast on magnetic resonance imaging may also be insufficient in making a reliable imaging diagnosis. These tumors can easily mimic hypervascular liver cancer, atypical hemangioma or metastases. This case report highlights the imaging features of this entity and also underlines that, this tumor should always be considered as a differential diagnosis for hypervascular tumors in cirrhotic patients. The current imaging paradigms for its diagnosis are also discussed.






References



1. Locker GY, Doroshow JH, Zwelling LA, and Chabner BA. The clinical features of hepatic angiosarcoma: a report of four cases and a review of the English literature. Medicine (Baltimore) 1979; 58:48-64
Get full text
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2. Kim HR, Rha SY, Cheon SH, Roh JK, Park YN, Yoo NC. Clinical features and treatment outcomes of advanced stage primary hepatic angiosarcoma. Ann Oncol 2009
Get full text
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3. Young RJ, Brown NJ, Reed MW, Hughes D, Woll PJ. Angiosarcoma Lancet Oncology 2010.Oct; 11(10):983-91. Doi: 10.1016/S1470-2045(10)70023-1 Epub 2010 May 25
Get full text
Find similar topics on Read this article on PubMed :: Find similar articles on Google scholarScholar :: Search for similar topics with the Radiology specific search engine Radiology search engine


4. Mani H, Van Thiel DH. Mesenchymal tumors of the liver. Clin Liver Dis 2001 Feb; 5(1):219-57, viii
Get full text
Find similar topics on Read this article on PubMed :: Find similar articles on Google scholarScholar :: Search for similar topics with the Radiology specific search engine Radiology search engine


5. Buetow PC, Buck JL, Ros PR, Goodman ZD. Malignant vascular tumours of the liver: radiologic-pathologic correlation. Radiographics 1994; 14:153-166
Get full text
Find similar topics on Read this article on PubMed :: Find similar articles on Google scholarScholar :: Search for similar topics with the Radiology specific search engine Radiology search engine


6. Timaran CH, Grandas OH, Bell JL. Hepatic angiosarcoma: long term survival after complete surgical removal. Am Surg 2000, 66(12):1153-1157
Get full text
Find similar topics on Read this article on PubMed :: Find similar articles on Google scholarScholar :: Search for similar topics with the Radiology specific search engine Radiology search engine


7. Molina E, Hernandez A. Clinical manifestations of primary hepatic angiosarcoma. Dig Dis Sci 2003; 48:677-82
Get full text
Find similar topics on Read this article on PubMed :: Find similar articles on Google scholarScholar :: Search for similar topics with the Radiology specific search engine Radiology search engine


8. Locker GY, Doroshow JH, Zwelling LA, Chabner BA. The clinical features of hepatic angiosarcoma: a report of four cases and a review of the English literature. Medicine (Baltimore) 1979; 58:48-64
Get full text
Find similar topics on Read this article on PubMed :: Find similar articles on Google scholarScholar :: Search for similar topics with the Radiology specific search engine Radiology search engine


9. Almogy G, Lieberman S. Clinical outcomes of surgical resections for primary liver sarcoma in adults: results from a single centre. Eur J Surg Oncol 2004; 30:421-427
Get full text
Find similar topics on Read this article on PubMed :: Find similar articles on Google scholarScholar :: Search for similar topics with the Radiology specific search engine Radiology search engine


10. Holden CA, Spittle MF, Jones EW. Angiosarcoma of the face and scalp, prognosis and treatment. Cancer 1987; 59:1046-1057
Get full text
Find similar topics on Read this article on PubMed :: Find similar articles on Google scholarScholar :: Search for similar topics with the Radiology specific search engine Radiology search engine


11. Maddox JC, Evans HL. Angiosarcoma of skin and soft tissue: a study of forty-four cases. Cancer 1981, 48:1907-1921
Get full text
Find similar topics on Read this article on PubMed :: Find similar articles on Google scholarScholar :: Search for similar topics with the Radiology specific search engine Radiology search engine


12. Maluf D, Cotterell A, Clark B, Stravitz T, Kauffman HM, Fisher RA. Hepatic angiosarcoma and liver transplantation: case report and literature review. Transplant Proc 2005; 37:2195-2199
Get full text
Find similar topics on Read this article on PubMed :: Find similar articles on Google scholarScholar :: Search for similar topics with the Radiology specific search engine Radiology search engine


13. Chin-Ying Chien, Cheng-cheng Hwang, Chun-nan Yeh, Huang-yang Chen, Jui-Teng Wu. Liver angiosarcoma, a rare liver malignancy, presented with intra-abdominal bleeding due to rupture- a case report. World Journal of Surgical Oncology .2012; 10:23 doi: 10.1186/1477-7819-10-23
Get full text
Find similar topics on Read this article on PubMed :: Find similar articles on Google scholarScholar :: Search for similar topics with the Radiology specific search engine Radiology search engine


14. Park YS, Kim JH, Kim KW, Lee IS, Yoon HK, Ko GY, Sung KB. Primary hepatic angiosarcoma: imaging findings and palliative treatment with transcatheter arterial chemoembolization or embolisation. Clin Radiol 2009 Aug; 64(8):779-85.doi: 10.1016/j.crad.2009.02.019
Get full text
Find similar topics on Read this article on PubMed :: Find similar articles on Google scholarScholar :: Search for similar topics with the Radiology specific search engine Radiology search engine


15. Bruegel M, Muenzel D. Hepatic angiosarcoma: cross-sectional imaging findings in seven patients with emphasis on dynamic contrast-enhanced and diffusion-weighted MRI. Abdom Imaging 2013 Aug; 38(4):745-54
Get full text
Find similar topics on Read this article on PubMed :: Find similar articles on Google scholarScholar :: Search for similar topics with the Radiology specific search engine Radiology search engine


16. Tordjman R, Eugene C, Clouet O. Hepato splenic angiosarcoma complicated by hemoperitoneum and disseminated intravascular coagulation. Treatment by arterial embolization and chemotherapy Gastroenterol Clin Biol
Get full text
Find similar topics on Read this article on PubMed :: Find similar articles on Google scholarScholar :: Search for similar topics with the Radiology specific search engine Radiology search engine


17. Kennedy A, Nag S, Salem R. Recommendations for radioembolization of hepatic malignancies using yttrium-90 microsphere brachytherapy: a consensus panel report from the radioembolization brachytherapy oncology consortium. Int J Radiat Oncol Biol Phys 2007; 68:13-23
Get full text
Find similar topics on Read this article on PubMed :: Find similar articles on Google scholarScholar :: Search for similar topics with the Radiology specific search engine Radiology search engine


18. Neff R, Abdel-Misih R, Khatri J. The toxicity of liver directed yttrium-90 microspheres in primary and metastatic liver tumors. Cancer Invest 2008; 26:173-177
Get full text
Find similar topics on Read this article on PubMed :: Find similar articles on Google scholarScholar :: Search for similar topics with the Radiology specific search engine Radiology search engine


19. Lee SW, Song CY. Hepatic angiosarcoma manifested as recurrent hemoperitoneum. World J Gastroenterology 2008; 14: 2935-2938
Get full text
Find similar topics on Read this article on PubMed :: Find similar articles on Google scholarScholar :: Search for similar topics with the Radiology specific search engine Radiology search engine


20. Leowardi C, Hormann Y, Hinz U, Wente MN, Hallscheidt P, Flechtenmacher C, Buchler MW, Friess H, Schwarzbach MH. Ruptured angiosarcoma of the liver treated by emergency catheter-directed embolization.World J Gastroenterol. 2006; 12:804-808
Get full text
Find similar topics on Read this article on PubMed :: Find similar articles on Google scholarScholar :: Search for similar topics with the Radiology specific search engine Radiology search engine


21. Heo SH, Jeong YY, Shin SS, Chung TW, Kang HK. Solitary Small Hepatic Angiosarcoma: Initial and Follow-up Imaging Findings. Korean Journal of Radiol 2007 Mar-Apr; 8(2):180-183
Get full text
Find similar topics on Read this article on PubMed :: Find similar articles on Google scholarScholar :: Search for similar topics with the Radiology specific search engine Radiology search engine


22. Peterson MS, Baron RL, Rankin SC. Hepatic angiosarcoma: findings on multiphasic contrast-enhanced helical CT do not mimic hepatic hemangioma. AJR Am J Roentgenol 2000; 175:165-170
Get full text
Find similar topics on Read this article on PubMed :: Find similar articles on Google scholarScholar :: Search for similar topics with the Radiology specific search engine Radiology search engine


23. Itai Y, Teraoka T. Angiosarcoma of the liver mimicking cavernous hemangioma on dynamic CT. J Comput AssistTomogr 1989;13:910-912
Get full text
Find similar topics on Read this article on PubMed :: Find similar articles on Google scholarScholar :: Search for similar topics with the Radiology specific search engine Radiology search engine


24. Suk Hee Heo, Yong Yeon Jeong, Sang Soo Shin, Tae Woong Chung, Heoung Keun Kang. Solitary Small Hepatic Angiosarcoma: Initial and Follow-up Imaging Findings .Korean J Radiol. 2007 Mar-Apr; 8(2): 180-183
Get full text
Find similar topics on Read this article on PubMed :: Find similar articles on Google scholarScholar :: Search for similar topics with the Radiology specific search engine Radiology search engine


25. El-Desouki Mahmoud, Mohamadiyeh Mohammad, Al-Rashed, Othman Saleh, Malabary Tajuddin, Al-Mofleh Ibrahim. TC-99m-labeled red blood cell scintigraphy in the investigation of patients with hepatic cavernous hemangioma. Saudi Journal of Gastroenterology 1999; 5(1): 27-31
Get full text
Find similar topics on Read this article on PubMed :: Find similar articles on Google scholarScholar :: Search for similar topics with the Radiology specific search engine Radiology search engine


26. Lee VW, O`Brien MJ. The specific diagnosis of hepatocellular carcinoma by scintigraphy. Cancer 1985; 56: 25-36
Get full text
Find similar topics on Read this article on PubMed :: Find similar articles on Google scholarScholar :: Search for similar topics with the Radiology specific search engine Radiology search engine


27. Kawamura E, Habu D, Ohfuji S, Fukushima W, Enomoto M. Clinical role of FDG-PET for HCC: relationship of glucose metabolic indicator to Japan Integrated Staging (JIS) score. Hepatogastroenterology 2008 Mar-Apr; 55(82-83):582-6 PubMed
Get full text
Find similar topics on Read this article on PubMed :: Find similar articles on Google scholarScholar :: Search for similar topics with the Radiology specific search engine Radiology search engine


28. Tetsuo Maeda, Ukihide Tateishi, Tadashi Hasegawa, Hidenori Ojima, Yasuaki Arai, Kazuro Sugimura. Case Report: Primary Hepatic Angiosarcoma on Coregistered FDG PET and CT Images. AJR June 2007 188:1615-1617; doi:10.2214/AJR.05.0830
Get full text
Find similar topics on Read this article on PubMed :: Find similar articles on Google scholarScholar :: Search for similar topics with the Radiology specific search engine Radiology search engine


29. Koyama T, Fletcher JG, Johnson CD, Kuo MS, Notohara K, Burgart LJ. Primary hepatic angiosarcoma: findings at CT and MR imaging. Radiology 2002 Mar; 222(3):667-73
Get full text
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