2024-03-29T10:29:31Z
https://www.radiologycases.com/index.php/radiologycases/oai
oai:journals.edurad.org:article/68
2009-03-04T10:31:53Z
radiologycases:NucMed
"081030 2008 eng "
1943-0922
dc
Lithium therapy: an unusual cause of elevated and diffuse radioactive iodine uptake.
Nyenwe, Ebenezer A
Fisher, Joseph
Vanmiddlesworth, Lester
Lithium carbonate, a widely used treatment for bipolar disorders, is associated with goiter, hypothyroidism and thyrotoxicosis. However, the effect of lithium to increase radioactive iodine uptake has received little attention, thus, making Lithium a confounding factor in the interpretation of thyroid radionuclide studies. We herein report a case of mistaken diagnosis of Graves' disease in a euthyroid, lithium-treated goitrous patient; due to elevated radioiodine uptake of 77.6%. We conclude that lithium therapy should be considered in the etiologic diagnoses of patients with goiter and homogenously elevated radioiodine uptake. It is pertinent to recognize this phenomenon in order to prevent unwarranted treatment with radioactive iodine or thionamides.
EduRad Publishing
2008-10-31 19:14:39
Peer-reviewed Article, Nuclear Medicine, Molecular Imaging
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https://www.radiologycases.com/index.php/radiologycases/article/view/68
Journal of Radiology Case Reports; Vol. 2 No. 4 (2008)
eng
Copyright (c)
oai:journals.edurad.org:article/70
2009-02-01T12:35:14Z
radiologycases:NucMed
"090131 2009 eng "
1943-0922
dc
Iodine 131 ablation of an obstructive lingual thyroid
Patel, Zeal
Johnson, Lester
A 48-year-old woman undergoing surgery could not be intubated because of an oropharyngeal mass. CT and MRI revealed a 3 cm possible lingual thyroid mass, confirmed by Iodine-123 SPECT/CT. The patient underwent successful Iodine-131 ablation and has done well on thyroid hormone-replacement therapy. This case also demonstrates how modern cross-sectional imaging like SPECT/CT can appropriately be used in the patient diagnosis and management, and is of additional interest for including pre- and post-therapy MRI documenting efficacy morphologically.
EduRad Publishing
2009-02-01 00:00:00
Peer-reviewed Article, Nuclear Medicine, Molecular Imaging
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https://www.radiologycases.com/index.php/radiologycases/article/view/70
Journal of Radiology Case Reports; Vol. 3 No. 2 (2009)
eng
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oai:journals.edurad.org:article/157
2009-04-04T19:36:16Z
radiologycases:NucMed
"090404 2009 eng "
1943-0922
dc
Detection of neoplastic meningitis in a patient with gastric cancer by thallium-201 SPECT
tonomura, Yasuyo
Kataoka, Hiroshi
Terashima, Mari
Shinkai, Takayuki
Ueno, Satoshi
We described the usefulness of thallium-201 SPECT in a patient with neoplastic meningitis (NM) from gastric carcinoma. Thallium-201 SPECT is of value for the diagnosis of cancer; retention of thallium-201 on delayed images strongly suggests malignancy. NM is a lethal, major neurologic complication of cancer. The standard for the diagnosis of NM is cytologic confirmation of malignant cells in CSF, but cytologic results are often negative (estimated false negative rate, 50%), even when NM is strongly suspected clinically. In patients with equivocal findings, our findings suggest that thallium-201 SPECT is one helpful tool for the detection of NM, particularly when associated with signet-ring cell carcinoma.
EduRad Publishing
2009-04-04 19:36:16
Peer-reviewed Article, Nuclear Medicine, Molecular Imaging
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https://www.radiologycases.com/index.php/radiologycases/article/view/157
Journal of Radiology Case Reports; Vol. 3 No. 4 (2009)
eng
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oai:journals.edurad.org:article/170
2009-11-05T22:25:41Z
radiologycases:NucMed
"090823 2009 eng "
1943-0922
dc
Expansive Masses Arising From The Clivus: The Role Of FDG-PET/CT In The Metabolic Assessment Of Skeletal Lesions
Cistaro, Angelina
Durando, Sabina
Pazè, Francesco
Limberti, Andrea
Cogoni, Maurizio
Junemann, Carola
Morra, Isabella
Valentini, Maria Consuelo
A patient with neurological symptoms underwent CT scan that showed a sellar and suprasellar mass with bone erosions, involving especially the clivus and the right petrous apex. The first diagnostic hypothesis was chordoma in relation to the mass position. The MRI showed a solid well-enhancing mass; moreover another circumscribed lesion, with similar signal pattern, was found in the left mandibular condyle. the signal and the presence of another lesion did not agree with diagnosis of chordoma. FDG-PET/CT study showed multiple pathological uptakes suggesting a metastatic disease. A trans-sphenoidal excisional biopsy was performed and the histopathological analysis showed a population of cells consistent with a plasmacell tumor, confirmed by the presence of a monoclonal gammopathy on blood analysis.
Our case suggests that FDG-PET/CT can modify the diagnostic and therapeutic procedures in myeloma, by evaluating the bone marrow involvement.
EduRad Publishing
2009-11-05 00:00:00
Peer-reviewed Article, Nuclear Medicine, Molecular Imaging
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https://www.radiologycases.com/index.php/radiologycases/article/view/170
Journal of Radiology Case Reports; Vol. 3 No. 11 (2009)
eng
Copyright (c)
oai:journals.edurad.org:article/242
2009-08-03T00:44:20Z
radiologycases:NucMed
"090726 2009 eng "
1943-0922
dc
Testicular relapse of non-Hodgkin Lymphoma noted on FDG-PET
Scotti, Stephen D
Laudadio, Jennifer
Testicular relapse of leukemia and lymphoma is a well-recognized phenomenon, with testicular relapse of lymphoma being more common in the adult population and leukemia relapse being more common in the pediatric population. With the advent of F-18 fluoro-2-deoxyglucose (FDG) positron emission tomography (PET) in the evaluation of lymphoma it is possible to evaluate testicular uptake of FDG and to detect primary testicular lymphoma or testicular relapse on the FDG-PET examination. Testicular relapse of non-Hodgkin lymphoma (NHL) detected on FDG-PET has been reported previously. We report an additional case in which there was testicular activity at presentation, a response to therapy (orchiectomy not performed) and then testicular relapse followed by orchiectomy. We review the literature with regard to testicular recurrence and testicular uptake of FDG-PET. There have been studies that have examined normal standardized uptake value maximum (SUVmax) values in the testicle, with normal values ranging from 2.81 (30-39 years) to 2.18 (80-89 years), depending upon age. However, it should be noted that there could be considerable variability in SUVmax values depending upon the units used (e.g. normalized to lean body mass vs. body weight) and depending upon examination variables such as dietary conditions, muscle uptake or extravasation of FDG. Elevated activity or lateralizing activity should be viewed with suspicion, with etiologies including primary testicular tumor, primary or secondary testicular lymphoma and metastatic disease with other etiologies less likely.
EduRad Publishing
2009-08-03 00:00:00
Peer-reviewed Article, Nuclear Medicine, Molecular Imaging
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https://www.radiologycases.com/index.php/radiologycases/article/view/242
Journal of Radiology Case Reports; Vol. 3 No. 8 (2009)
eng
Copyright (c)
oai:journals.edurad.org:article/278
2009-08-03T00:44:20Z
radiologycases:NucMed
"090726 2009 eng "
1943-0922
dc
Symptomatic Calvarial Cavernous Hemangioma: Presurgical Confirmation by Scintigraphy
Gordhan, Ajeet
Soliman, John
Malpani, Ajay
Pegg III, Edward
Hemangiomas are rare tumors in the calvarium and represent 2% of osseous calvarial lesions. Dynamic Tc-99m RBC blood pool scintigraphy has a high positive predictive value for cavernous hemangiomas of the liver. This scintigraphic technique can be used for identifying cavernous hemangiomas at other anatomic sites. We present a case in which a tagged RBC blood pool scan was used for further characterizing a symptomatic calvarial lesion as a cavernous hemangioma. This avoided an unnecessary workup for metastatic disease and was valuable in surgical planning for anticipated increased intra-operative blood loss. Histological confirmation of a cavernous hemangioma was made after surgical resection.
EduRad Publishing
2009-08-03 00:00:00
Peer-reviewed Article, Nuclear Medicine, Molecular Imaging
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https://www.radiologycases.com/index.php/radiologycases/article/view/278
Journal of Radiology Case Reports; Vol. 3 No. 8 (2009)
eng
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oai:journals.edurad.org:article/285
2009-09-05T20:07:14Z
radiologycases:NucMed
"090823 2009 eng "
1943-0922
dc
SPECT/CT imaging of a retroperitoneal nodule in a patient with history of infiltrating renal urothelial carcinoma
Schonlau, Duane
Barker, David
Hall, Nathan
A 62 year old woman status post radical nephroureterectomy for high grade urothelial carcinoma was found on CT to have a 1 cm retroperitoneal nodule in the nephrectomy bed. The nodule's differential diagnosis included recurrent urothelial carcinoma versus relocation of the patient's splenule seen on earlier CT imaging. We report using SPECT/CT with Tc-99m labeled denatured red blood cells to definitively diagnose the nodule as a relocated splenule.
EduRad Publishing
2009-09-05 20:07:14
Peer-reviewed Article, Nuclear Medicine, Molecular Imaging
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text/html
https://www.radiologycases.com/index.php/radiologycases/article/view/285
Journal of Radiology Case Reports; Vol. 3 No. 9 (2009)
eng
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oai:journals.edurad.org:article/310
2010-02-06T22:57:29Z
radiologycases:NucMed
"100124 2010 eng "
1943-0922
dc
Calcified Lymph Nodes Causing Clinically Relevant Attenuation Correction Artifacts on PET/CT Imaging
Mehta, Amar Singh
Mehta, Ajeet
Laymon, Charles
Blodgett, Todd
There are several artifacts unique to PET/CT imaging, with CT-based attenuation correction (AC) artifacts being among the most commonly reported. AC artifacts from calcified lymph nodes represent clinically significant and easily misinterpreted PET/CT artifacts that have received little attention in the literature. In this case series, we report three cases of calcified lymph nodes causing an AC artifact and one case of a highly calcified lymph node without an AC artifact. All three cases of calcified lymph nodes causing an AC artifact would have resulted in a change in patient staging, and likely management, if the nodes had been misinterpreted as malignant nodes. In PET/CT imaging, this artifact needs to be considered as a potential cause of apparent FDG activity when calcified lymph nodes are present on the CT portion of a PET/CT study in order to avoid misinterpretation and potential patient mismanagement.
EduRad Publishing
2010-02-06 00:00:00
Peer-reviewed Article, Nuclear Medicine, Molecular Imaging
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https://www.radiologycases.com/index.php/radiologycases/article/view/310
Journal of Radiology Case Reports; Vol. 4 No. 2 (2010)
eng
Copyright (c)
oai:journals.edurad.org:article/314
2009-10-06T20:40:56Z
radiologycases:NucMed
"090927 2009 eng "
1943-0922
dc
Asymmetric 18F-FDG Uptake in the Infradiaphragmatic Brown Adipose Tissue (BAT) Mimicking Adrenal Metastasis: A Relatively Rare Site of Brown Fat and a Potential Source for False Positive FDG-PET Study
Basu, Sandip
Tiwari, Bijaynath P
FDG uptake in the metabolically active brown adipose tissue (BAT) is a source of significant concern while interpreting FDG-PET studies. It is also of great interest due to its potential implications for obesity research. In this communication, we describe hitherto unreported asymmetric BAT uptake in the abdomen, persisting after diazepam intervention in the repeat PET study on a separate day. The patient did not have any evidence of disease even at 24 months' follow up. The present case is a useful addition to the current body of literature of false positive FDG-PET due to BAT uptake in unusual location and underscores the importance of high index of suspicion and careful correlation, whenever one comes across an unusual PET finding in a given clinical situation. This assumes important diagnostic value particularly when it coexists in the setting of malignancy where the disease can be falsely upstaged by misinterpretation. The literature relevant to the report is discussed and a schema is suggested for correct interpretation.
EduRad Publishing
2009-10-06 00:00:00
Peer-reviewed Article, Nuclear Medicine, Molecular Imaging
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https://www.radiologycases.com/index.php/radiologycases/article/view/314
Journal of Radiology Case Reports; Vol. 3 No. 10 (2009)
eng
Copyright (c)
oai:journals.edurad.org:article/352
2010-03-10T23:27:10Z
radiologycases:NucMed
"100304 2010 eng "
1943-0922
dc
FDG uptake in sternoclavicular joint synovitis: Mimic of internal mammary adenopathy.
Lin, Eugene
False-positive FDG uptake has been noted in a wide range of benign processes. In this report, we describe a case of FDG uptake in unilateral sternoclavicular synovitis which mimicked an internal mammary node in appearance. Knowledge of this potential false-positive is particularly important in breast cancer patients with a propensity of internal mammary nodal metastases.
EduRad Publishing
2010-03-10 23:27:10
Peer-reviewed Article, Nuclear Medicine, Molecular Imaging
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https://www.radiologycases.com/index.php/radiologycases/article/view/352
Journal of Radiology Case Reports; Vol. 4 No. 3 (2010)
eng
Copyright (c)
oai:journals.edurad.org:article/374
2010-04-04T19:45:24Z
radiologycases:NucMed
"100328 2010 eng "
1943-0922
dc
FDG PET/CT diagnosis of hepatic lymphoma mimicking focal fatty infiltration on CT
Lin, Eugene
Lee, Marie
Agoff, Nicholas
Areas of hypoattenuation in the liver which do not have mass effect are typically thought to represent focal fatty infiltration. Rarely, tumors can present without mass effect in the liver. We present a case in which areas of liver hypoattenuation which were initially thought to represent focal fatty infiltration on CT due to lack of mass effect had abnormal uptake on a FDG PET/CT exam; these areas were due to secondary hepatic involvement from non-Hodgkin's lymphoma.
EduRad Publishing
2010-04-04 19:45:24
Peer-reviewed Article, Nuclear Medicine, Molecular Imaging
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https://www.radiologycases.com/index.php/radiologycases/article/view/374
Journal of Radiology Case Reports; Vol. 4 No. 4 (2010)
eng
Copyright (c)
oai:journals.edurad.org:article/381
2010-07-09T21:27:59Z
radiologycases:NucMed
"100627 2010 eng "
1943-0922
dc
Imaging Keratitis-Icthyosis-Deafness (KID) syndrome with FDG-PET (F18-fluorodeoxiglucose-Positron Emission Tomography)
Mari Aparici, MD, Carina
Arcienega, Daniela
Cho, Eric
Hawkins, Randy
Keratitis-Icthyosis-Deafness (KID) syndrome is a rare dysplasia characterized by vascularizing keratitis, congenital sensorineural hearing-loss, and progressive erythrokeratoderma. To our knowledge, this is the first KID syndrome imaged with FDG-PET in the literature. This paper is intended to help familiarize with the FDG abnormalities related to this rare entity.
EduRad Publishing
2010-07-09 21:27:59
Peer-reviewed Article, Nuclear Medicine, Molecular Imaging
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https://www.radiologycases.com/index.php/radiologycases/article/view/381
Journal of Radiology Case Reports; Vol. 4 No. 7 (2010)
eng
Copyright (c)
oai:journals.edurad.org:article/656
2011-04-13T20:42:16Z
radiologycases:NucMed
"110409 2011 eng "
1943-0922
dc
Extraperitoneal Urinary Bladder Perforation Detected by FDG PET/CT
Wosnitzer, Brian
Mirtcheva, Rosna
Accurate localization of areas of increased metabolic activity on PET only imaging can be challenging. Fusion of PET with CT imaging provides anatomic detail which aids in localization of functional information. As a result, the overall sensitivity and specificity of information provided by PET or CT alone is improved with combined PET/CT resulting in improved diagnosis and patient management. We report a case of an unexpected emergent finding of urinary bladder perforation on PET/CT to stress the importance of accurately interpreting the anatomic and functional data. To our knowledge, diagnosis of bladder perforation on PET/CT has not been previously reported in the literature. Failure to recognize such complications may lead to adverse outcomes.
EduRad Publishing
2011-04-13 20:42:16
Peer-reviewed Article, Nuclear Medicine, Molecular Imaging
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text/html
https://www.radiologycases.com/index.php/radiologycases/article/view/656
Journal of Radiology Case Reports; Vol. 5 No. 4 (2011)
eng
Copyright (c)
oai:journals.edurad.org:article/697
2011-05-14T16:25:15Z
radiologycases:NucMed
"110508 2011 eng "
1943-0922
dc
Particle Disease on Fluoride-18 (NaF) PET/CT imaging
Kuo, Jonathan
Foster, Cameron
Shelton, David
Particle disease is a loss of bone that commonly occurs five years after arthroplasty. The cause is secondary to microabrasive wear and shedding of any portion of the prosthesis, and the microscopic foreign bodies activate inflammation which can lead to pain. This report describes the imaging findings of an 80-year-old female with particle disease detected with 18F-fluoride PET/CT.
EduRad Publishing
2011-05-14 16:25:15
Peer-reviewed Article, Nuclear Medicine, Molecular Imaging
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text/html
https://www.radiologycases.com/index.php/radiologycases/article/view/697
Journal of Radiology Case Reports; Vol. 5 No. 5 (2011)
eng
Copyright (c)
oai:journals.edurad.org:article/711
2011-06-18T16:30:53Z
radiologycases:NucMed
"110607 2011 eng "
1943-0922
dc
Impact of geometric mean imaging in the accurate determination of partial function in MAG3 renal scanning in a patient with retroperitoneal mass
Takesh, Mustafa
Zechmann, Christian M
Haufe, Sabine
Giesel, Frederik L
Kratochwil, Clemens
Liposarcoma frequently occurs in the retroperitoneum and lower extremities, accounting for 20% of all mesenchymal malignancies. Liposarcomas vary by histology and can be classified into four types. Those four types are well differentiated, myxoid/round cell, pleomorphic and dedifferentiated. Due to retroperitoneal location of this tumor, it is expected to affect the kidney position. Renography has provided a unique tool for noninvasive evaluation of various functional parameters e.g. relative renal function. Most renography studies are carried out using the posterior view, under the assumption that the depths of both kidneys are similar so that the radiotracer counts in the region of interest will be attenuated to the same extent. Errors in estimation of the relative renal function may arise if the kidneys are at different depths e.g. secondary to a pushing tumor. Geometric mean imaging from combined anterior and posterior views helps to overcome this issue. This case shows the impact of geometric mean imaging in the truthful determination of partial function in patients with retroperitoneal liposarcoma.
EduRad Publishing
2011-06-18 16:30:53
Peer-reviewed Article, Nuclear Medicine, Molecular Imaging
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https://www.radiologycases.com/index.php/radiologycases/article/view/711
Journal of Radiology Case Reports; Vol. 5 No. 6 (2011)
eng
Copyright (c)
oai:journals.edurad.org:article/722
2011-07-10T19:37:48Z
radiologycases:NucMed
"110704 2011 eng "
1943-0922
dc
Retroperitoneal Fibrosis as a Cause of Positive FDG PET/CT
Mehta, Amar S.
Blodgett, Todd M.
This article educates the reader on idiopathic retroperitoneal fibrosis and emphasizes the importance of considering conditions that mimic this disease on PET/CT through an illustrative case of a 58 year-old man presenting with intermittent abdominal, back, and scrotal pain undergoing successive PET/CT scans, both for diagnosis and following treatment.
EduRad Publishing
2011-07-10 19:37:48
Peer-reviewed Article, Nuclear Medicine, Molecular Imaging
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text/html
https://www.radiologycases.com/index.php/radiologycases/article/view/722
Journal of Radiology Case Reports; Vol. 5 No. 7 (2011)
eng
Copyright (c)
oai:journals.edurad.org:article/758
2011-09-18T19:29:53Z
radiologycases:NucMed
"110914 2011 eng "
1943-0922
dc
Inflammatory Pseudotumor of the Spleen: Review of clinical presentation and diagnostic methods
Yarmohammadi, Hooman
Nakamoto, Dean
Faulhaber, Peter F.
Miedler, John
Azar, Nami
We describe a 91-year-old woman with a clinical history of invasive ductal carcinoma of the breast diagnosed in 1991 who was admitted because of dizziness, poor appetite, and some swelling and tenderness over her cheeks. The patient's initial work up revealed a 5-cm well-demarcated hypodense solid lesion in her spleen with abnormally intense uptake on PET/CT scan raising suspicion for malignancy i.e. breast metastasis versus lymphoma. Further review demonstrated the presence of this splenic lesion, though slightly smaller, on a CT scan from ten years earlier (2000). An ultasonographic guided core needle splenic biopsy was performed and the pathology result revealed histological findings compatible with inflammatory pseudotumor of the spleen. As a result, unnecessary splenectomy was avoided.
EduRad Publishing
2011-09-18 19:29:53
Peer-reviewed Article, Nuclear Medicine, Molecular Imaging
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https://www.radiologycases.com/index.php/radiologycases/article/view/758
Journal of Radiology Case Reports; Vol. 5 No. 9 (2011)
eng
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oai:journals.edurad.org:article/844
2012-02-19T18:19:05Z
radiologycases:NucMed
"120214 2012 eng "
1943-0922
dc
False Positive GI Bleed on Tc-99m RBC Scintigraphy Due to Ileal Varices
Chen, Paul
Brown, Richard
Tc-99m labeled RBC scintigraphy is commonly employed in the evaluation of acute gastrointestinal bleeding. On Tc-99m RBC studies gastrointestinal bleeding is seen as an initial focus of increased radiotracer activity that on subsequent images increases in intensity and changes position in a pattern that conforms to segments of bowel. We report a case of a patient with multiple episodes of hematochezia that presented with lower gastrointestinal hemorrhage. A Tc-99m labeled RBC scan was performed and the findings suggested a GI bleed. However, subsequent angiography revealed prominent ileal varices simulating an acute bleed. Although most varices fill promptly and should not be misinterpreted as a focus of hemorrhage, slow filling varices can simulate an acute bleed and lead to a false positive interpretation.
EduRad Publishing
2012-02-19 18:19:05
Peer-reviewed Article, Nuclear Medicine, Molecular Imaging
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text/html
https://www.radiologycases.com/index.php/radiologycases/article/view/844
Journal of Radiology Case Reports; Vol. 6 No. 2 (2012)
eng
Copyright (c)
oai:journals.edurad.org:article/904
2012-03-17T19:19:17Z
radiologycases:NucMed
"120311 2012 eng "
1943-0922
dc
F-18 FDG PET/CT and Tc-99m Sulfur Colloid SPECT imaging in the diagnosis and treatment of a case of dual solitary fibrous tumors of the retroperitoneum and pancreas
Azadi, Javad
Subhawong, Andrea
Durand, Daniel James
Although FDG PET is increasingly used for the staging of many types of sarcoma, little has been written regarding the FDG PET imaging characteristics of solitary fibrous tumor. We report a patient undergoing FDG PET/CT surveillance for squamous cell carcinoma of the tongue who was incidentally found to have two soft tissue masses in the retroperitoneum and pancreatic tail. Due to their low degree of FDG avidity, they were followed conservatively for approximately one year as they gradually increased in size. Technetium-99m sulfur colloid SPECT helped confirm that the pancreatic tail mass was not a splenule, after which both lesions were surgically resected and found to be extrathoracic solitary fibrous tumors without malignant features. These findings suggest that, as with other low-grade sarcomas, benign extrathoracic solitary fibrous tumors exhibit relatively little glycolytic metabolism in vivo.
EduRad Publishing
2012-03-17 19:19:17
Peer-reviewed Article, Nuclear Medicine, Molecular Imaging
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https://www.radiologycases.com/index.php/radiologycases/article/view/904
Journal of Radiology Case Reports; Vol. 6 No. 3 (2012)
eng
Copyright (c)
oai:journals.edurad.org:article/1109
2012-11-23T21:17:34Z
radiologycases:NucMed
"121119 2012 eng "
1943-0922
dc
Flare Response versus Disease Progression in Patients with Non-small Cell Lung Cancer.Flare Response versus Disease Progression in Patients with Non-small Cell Lung Cancer
Al-Nabhani, Khalsa
Syed, Rizwan
Haroon, Athar
Almukhailed, Omar
Bomanji, Jamshed
We present a case report of a patient with metastatic non-small cell lung cancer (NSCLC) who had a serial of fluorine-18 fluorodeoxyglucose positron emission tomography/computed tomography (18F-FDG PET/CT) scans for assessment of response to treatment. A restaging 18F-FDG PET/CT scan after six cycles showed increased FDG activity in the bone lesions with reduced activity in the lung and liver lesions. The increased bone activity was considered to be due to flare phenomenon rather than metastasis. A short interval follow up scan after 1 month was advised to confirm this interpretation but this repeat scan showed disease relapse. Although the flare phenomenon does exist, caution should be exercised in attributing increased tracer uptake in the lesions in patients with adenocarcinoma of lung and especially those who have received erlotinib during the course of their treatment. Distinguishing the 'flare phenomenon' and 'disease progression' is at times difficult but is important since misdiagnosis may result in an unnecessary delay in patient management.
EduRad Publishing
2012-11-23 21:17:34
Peer-reviewed Article, Nuclear Medicine, Molecular Imaging
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https://www.radiologycases.com/index.php/radiologycases/article/view/1109
Journal of Radiology Case Reports; Vol. 6 No. 11 (2012)
eng
Copyright (c)
oai:journals.edurad.org:article/1144
2012-09-30T20:26:51Z
radiologycases:NucMed
"120925 2012 eng "
1943-0922
dc
Unusual Concentration of Tc-99m methylendiphosphonate in Rhabdomyosarcoma
Franco, Arie
Henderson, Patrick Ryan
McDonough, Colleen Hope
Extraosseous accumulation of bone-seeking agents is rare, but has been previously reported in pediatric sarcomas and neuroblastomas. We present an unusual case of a 5-month-old male with an abdominal mass observed clinically by his parents and referring pediatrician. Contrast abdominal computerized tomography confirmed the presence of a large pelvic mass that was diagnosed pathologically as embryonal rhabdomyosarcoma. A bone scintigraphy that was performed for staging of the disease revealed accumulation of the radiopharmaceutical in the tumor. There was no evidence for skeletal metastatic disease. This case further demonstrates the nonspecificity of soft-tissue tumor uptake on bone scintigraphy.
EduRad Publishing
2012-09-30 20:26:51
Peer-reviewed Article, Nuclear Medicine, Molecular Imaging
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https://www.radiologycases.com/index.php/radiologycases/article/view/1144
Journal of Radiology Case Reports; Vol. 6 No. 9 (2012)
eng
Copyright (c)
oai:journals.edurad.org:article/1163
2012-10-27T20:41:21Z
radiologycases:NucMed
"121023 2012 eng "
1943-0922
dc
Nuclear scintigraphy findings for Askin tumor with In111-pentetreotide, Tc99m-MIBI and F18-FDG.
Chen, Johnathan
Chang, Johanna
Lew, Peter
Vasinrapee, Panukorn
Shim, John J
Askin tumor is a rare disease which had previously been reported as being thallium-201 and gallium-67 avid. Varying data regarding 18F-fluorodeoxyglucose metabolism has been described with Ewing family of soft tissue tumors. In this case, we present a patient found to have an Askin tumor of the left chest wall which demonstrated indium-111 pentetreotide and technetium-99m MIBI avidity. The lesion did not show 18F-fluorodeoxyglucose hypermetabolism in this case despite the aggressiveness of the tumor. The patient was treated with surgical excision of the tumor and chemotherapy. Subsequently, contrast enhanced CT, indium-111 pentetreotide and technetium 99m-MIBI showed that the lesion had regressed. These findings suggest that Askin tumor can demonstrate Indium-111 pentetreotide and technetium 99m-MIBI uptake and need not be hypermetabolic on 18F-fluorodeoxyglucose exam.
EduRad Publishing
2012-10-27 20:41:21
Peer-reviewed Article, Nuclear Medicine, Molecular Imaging
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https://www.radiologycases.com/index.php/radiologycases/article/view/1163
Journal of Radiology Case Reports; Vol. 6 No. 10 (2012)
eng
Copyright (c)
oai:journals.edurad.org:article/1194
2012-12-31T19:40:04Z
radiologycases:NucMed
"121226 2012 eng "
1943-0922
dc
Rare lymphoid malignancies of the breast: report of two cases illustrating potential diagnostic techniques
lacanfora, annamaria
orazio, schillaci
laura, travascio
sara, ceccarelli
giovanni, simonetti
Two cases of lymphoid malignancy involving the breast are herein presented. Both patients were admitted with a palpable breast mass. Ultrasound demonstrated hypoechoic, ill-defined lesions of the breast in both patients; mammogram also showed spiculated breast densities. Both patients underwent core biopsy, which revealed lymphomatous cells. Total-body evaluation was also performed by computed tomography and positron emission tomography/computed tomography revealing no other fluorodeoxyglucose-avid foci in the first case and supra and subdiaphragmatic disease in the second one.
EduRad Publishing
2012-12-31 19:40:04
Peer-reviewed Article, Nuclear Medicine, Molecular Imaging
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text/html
https://www.radiologycases.com/index.php/radiologycases/article/view/1194
Journal of Radiology Case Reports; Vol. 6 No. 12 (2012)
eng
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oai:journals.edurad.org:article/1328
2014-06-30T22:42:04Z
radiologycases:NucMed
"140626 2014 eng "
1943-0922
dc
The Hypermetabolic Giant: 18F-FDG avid Giant Cell Tumor identified on PET-CT
O'Connor, Wendi
Quintana, Megan T.
Smith, Scott V
Willis, Monte S
McCartney, William
An 87 year-old white female presented with a two-year history of intermittent discomfort in her left foot. PET-CT identified intense18F-fluorodeoxyglucose (FDG) uptake corresponding to the lesion. Histology of a fine needle aspiration and open biopsy were consistent with a benign giant cell tumor (GCT) of the bone. GCT of bone is an uncommon primary tumor typically presenting as a benign solitary lesion that arises in the end of the long bones. While GCT can occur throughout the axial and appendicular skeleton, it is exceedingly uncommon in the bone of the foot. While 18F-FDG has been established in detecting several malignant bone tumors, benign disease processes may also be identified. The degree of 18F-FDG activity in a benign GCT may be of an intensity that can be mistakenly interpreted as a malignant lesion. Therefore, GCT of the bone can be included in the differential diagnosis of an intensely 18F-FDG-avid neoplasm located within the tarsal bones.
EduRad Publishing
2014-06-30 22:42:04
Peer-reviewed Article, Nuclear Medicine, Molecular Imaging
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text/html
text/html
https://www.radiologycases.com/index.php/radiologycases/article/view/1328
Journal of Radiology Case Reports; Vol. 8 No. 6 (2014)
eng
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oai:journals.edurad.org:article/1661
2014-01-31T23:02:21Z
radiologycases:NucMed
"140128 2014 eng "
1943-0922
dc
Bilateral cryptorchidism mimicking external iliac lymphadenopathy in a patient with leg melanoma: role of FDG-PET and ultrasound in management
Kyle, Samuel
Law, W Phillip
Cryptorchidism is the most common congenital anomaly present at birth in males. Spontaneous testicular descent occurs in the majority of patients, typically before 6 months of age. Radiology plays an important role, predominantly in the assessment of the nonpalpable testis, with ultrasound being the most commonly employed modality. Magnetic resonance imaging is however the most accurate modality for the assessment of the nonpalpable testis, particularly with the use of fat suppressed T2 and diffusion weighted sequences. While traditionally treated in infancy, the untreated or occult form can radiologically be mistaken for lymphadenopathy. Fluorodeoxyglucose (FDG) positron emission tomography can play an important role in differentiating cryptorchidism from lymphadenopathy, most commonly in patients with known malignancy, although FDG uptake can be variable. We present a case of bilateral cryptorchidism in an adult male which masqueraded as lymphadenopathy in a patient with lower limb melanoma.
EduRad Publishing
2014-01-31 20:47:02
Peer-reviewed Article, Nuclear Medicine, Molecular Imaging
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text/html
https://www.radiologycases.com/index.php/radiologycases/article/view/1661
Journal of Radiology Case Reports; Vol. 8 No. 1 (2014)
eng
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oai:journals.edurad.org:article/1869
2015-04-29T18:41:42Z
radiologycases:NucMed
"150419 2015 eng "
1943-0922
dc
18-FDG Uptake in Pulmonary Dirofilariasis
Stone, Michael
Dalal, Ishani
Stone, Chad
Dalal, Bhavin
Solitary pulmonary nodules are a common finding on chest radiography and CT. We present the case of an asymptomatic 59-year-old male found to have a 13 mm left upper lobe nodule on CT scan. The patient was asymptomatic and the CT was performed to follow up mediastinal and hilar lymphadenopathy that had been stable on several previous CT scans. He had a history of emphysema and reported a 15 pack-year smoking history. PET-CT was performed which demonstrated mild 18-FDG uptake within the nodule. Given his age and smoking history, malignancy was a consideration and he underwent a wedge resection. Pathological examination revealed a necrobiotic granulomatous nodule with a central thrombosed artery containing a parasitic worm with internal longitudinal ridges and abundant somatic muscle, consistent with pulmonary dirofilariasis. Dirofilaria immitis, commonly known as the canine heartworm, rarely affects humans. On occasion it can be transmitted to a human host by a mosquito bite. There are two major clinical syndromes in humans: pulmonary dirofilariasis and subcutaneous dirofilariasis. In the pulmonary form, the injected larvae die before becoming fully mature and become lodged in the pulmonary arteries.
EduRad Publishing
2015-04-29 18:41:42
Peer-reviewed Article, Nuclear Medicine, Molecular Imaging
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text/html
text/html
https://www.radiologycases.com/index.php/radiologycases/article/view/1869
Journal of Radiology Case Reports; Vol. 9 No. 4 (2015)
eng
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oai:journals.edurad.org:article/2060
2014-11-28T14:03:51Z
radiologycases:NucMed
"141124 2014 eng "
1943-0922
dc
FDG Positron Emission Tomography and Computed Tomography Demonstration of Carcinoma Arising in an Epiphrenic Diverticulum
Eluvathingal Muttikkal, Thomas Jose
Shami, Vanessa M
Jones, David R
Rehm, Patrice K
Esophageal carcinoma arising within an epiphrenic diverticulum is rare. We describe a case of a carcinoma in a long-standing epiphrenic diverticulum in a 62-year-old patient. Fluorine-18-2-Fluoro-2-Deoxy-D-Glucose Positron Emission Tomography and Computed Tomography, and endoscopic ultrasound revealed a hypermetabolic mass within the diverticulum. A preoperative diagnosis was made via endoscopic biopsy. The patient underwent Ivor-Lewis esophagectomy. He remains well and free of recurrence 18 months after surgery.
EduRad Publishing
2014-11-28 14:03:51
Peer-reviewed Article, Nuclear Medicine, Molecular Imaging
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text/html
text/html
https://www.radiologycases.com/index.php/radiologycases/article/view/2060
Journal of Radiology Case Reports; Vol. 8 No. 11 (2014)
eng
Copyright (c)
oai:journals.edurad.org:article/2220
2015-06-15T20:19:41Z
radiologycases:NucMed
"150610 2015 eng "
1943-0922
dc
Sialadenitis following low dose I-131 diagnostic thyroid scan with Thyrogen® (recombinant human thyroid stimulating hormone - thyrotropin alfa)
Gonzalez, Marta E
http://www.medicine.virginia.edu/clinical/departments/radiology/home
Eluvathingal Muttikkal, Thomas Jose
http://www.medicine.virginia.edu/clinical/departments/radiology/home
Rehm, Patrice K
http://www.medicine.virginia.edu/clinical/departments/radiology/home
Salivary dysfunction and sialadenitis are well known complications of radioiodine treatment for thyroid cancer. The parotid gland is more frequently affected and the salivary gland injury is dose related. The symptoms may develop shortly after therapeutic Iodine 131(I-131) administration or months later and progress with time. The development of unilateral parotiditis following a low dose, diagnostic I-131 scan performed following Thyrogen stimulation in a patient without prior history of sialadenitis is rare in our experience, and has not been reported in the medical literature.
EduRad Publishing
2015-06-15 20:19:41
Peer-reviewed Article, Nuclear Medicine, Molecular Imaging
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text/html
https://www.radiologycases.com/index.php/radiologycases/article/view/2220
Journal of Radiology Case Reports; Vol. 9 No. 6 (2015)
eng
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oai:journals.edurad.org:article/2264
2015-02-28T14:55:22Z
radiologycases:NucMed
"150223 2015 eng "
1943-0922
dc
Systemic Mastocytosis: A Rare Cause of Single Vertebral Body Uptake on Bone Scan
Chehab, Monzer
Copelan, Alexander
Al-faham, Zaid
Bahoura, Lawrence
Wong, Ching Yee Oliver
Systemic Mastocytosis is a rare condition characterized by the abnormal proliferation of Mast Cells. Presentation as a solitary vertebral body lesion is extremely uncommon and may be confused with more ominous conditions such as metastasis. Familiarity with the condition can heighten clinical suspicion, direct tissue diagnosis, guide management and indicate appropriate follow up. We present a case of a 64-year-old woman undergoing staging for recently diagnosed breast cancer who was found to have Systemic Mastocytosis of a single vertebral body.
EduRad Publishing
2015-02-28 14:55:22
Peer-reviewed Article, Nuclear Medicine, Molecular Imaging
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text/html
https://www.radiologycases.com/index.php/radiologycases/article/view/2264
Journal of Radiology Case Reports; Vol. 9 No. 2 (2015)
eng
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oai:journals.edurad.org:article/2419
2015-08-30T19:06:02Z
radiologycases:NucMed
"150827 2015 eng "
1943-0922
dc
Maxillary mesenchymal chondrosarcoma presenting with epistaxis in a child
Uppaluri, Srinivas Anand Swaroop
Yin, Loi Hoi
Goh, Giap Hean
Mesenchymal chondrosarcomas are a rare variant of primary chondrosarcomas and can pose a diagnostic dilemma, especially when the features on conventional imaging are equivocal for an aggressive lesion. There is very little PET-CT experience in mesenchymal chondrosarcomas as per the literature and to the best of our knowledge, we are the first to describe a maxillary mesenchymal chondrosarcoma on PET-CT imaging. We report a case where PET-CT not only complemented conventional imaging in suspecting a malignant osseous lesion, but also was indicative of the grade of the tumor.
EduRad Publishing
2015-08-30 19:06:02
Peer-reviewed Article, Nuclear Medicine, Molecular Imaging
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text/html
text/html
https://www.radiologycases.com/index.php/radiologycases/article/view/2419
Journal of Radiology Case Reports; Vol. 9 No. 8 (2015)
eng
Copyright (c)
oai:journals.edurad.org:article/2721
2016-06-29T22:56:07Z
radiologycases:NucMed
"160624 2016 eng "
1943-0922
dc
Small bowel perforation: a rare complication of ventriculoperitoneal shunt placement
Bourm, Kelsey Steven
Pfeifer, Cory
Zarchan, Adam
Small bowel perforation is a rare complication of ventriculoperitoneal (VP) shunt placement. When seen, it most commonly affects the stomach or colon. We describe a case and image findings of an 8-year-old female who presented with sepsis and erosion of the VP shunt into the small bowel. The imaging findings were confirmed surgically. We also provide an overview of the current literature discussing previously reported cases, clinical features, and treatment.
EduRad Publishing
2016-06-29 00:00:00
Peer-reviewed Article, Nuclear Medicine, Molecular Imaging
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text/html
https://www.radiologycases.com/index.php/radiologycases/article/view/2721
Journal of Radiology Case Reports; Vol. 10 No. 6 (2016)
eng
Copyright (c)
oai:journals.edurad.org:article/4193
2021-03-31T16:32:16Z
radiologycases:NucMed
"210323 2021 eng "
1943-0922
dc
The role of whole-Body fluorine-18-fluorodeoxyglucose positron emission tomography in staging and surveillance of mucosa-associated lymphoid tissue
Zhang, Shunqing
Rossetti-Chung, Allen
Sood, Sumit
Terezakis, Stephanie
We present the case of a 79-year-old male, who was initially treated for mucosa-associated lymphoid tissue lymphoma (MALT lymphoma) of the right eyelid, and later for disease relapse in the stomach. During follow up, he was noted to have developed left arm nodules just medial to the proximal biceps muscle, which were found to be multiply enlarged lymph nodes on subsequent ultrasound imaging. Excisional biopsy of these nodes revealed MALT lymphoma. He was initially referred for consideration of radiation, but a restaging F-18 fluorodeoxyglucose positron emission tomography integrated with computed tomography (F-18 FDG PET/CT) further identified a focus of suspicious uptake in left calf, which was later also biopsy proven to be MALT lymphoma. His disease was upstaged as the result of this later finding, and the overall recommendation for treatment changed to favor systemic treatment with Rituximab.
EduRad Publishing
2021-03-31 16:27:38
Peer-reviewed Article, Nuclear Medicine, Molecular Imaging
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text/html
https://www.radiologycases.com/index.php/radiologycases/article/view/4193
Journal of Radiology Case Reports; Vol. 15 No. 3 (2021)
eng
Copyright (c)
oai:journals.edurad.org:article/4411
2024-01-24T07:54:27Z
radiologycases:NucMed
"231031 2023 eng "
1943-0922
dc
Imaging in hepatopulmonary syndrome- case report. A multicenter approach during the coronavirus pandemic
Ahmmed, Afsara Anisa
Department of Radiology, University Hospitals Bristol and Weston Foundation Trust, Bristol, UK https://orcid.org/0000-0002-7412-1265
Kulshrestha, Randeep
Department of Radiology, University Hospitals Bristol and Weston Foundation Trust, Bristol, UK
A 60-year-old lady with alcoholic liver disease developed central cyanosis and orthodeoxia. A technetium-99m macro-aggregated albumin lung perfusion scan and contrast echocardiogram were performed. A 13% right to left shunt was calculated from the macro-aggregated albumin scan. There were more bubbles in the left heart than the right at the end of the contrast echocardiogram. Hepatopulmonary syndrome was therefore diagnosed. The patient had a liver transplant five days after these investigations. Further discussion about hepatopulmonary syndrome will be provided.
Normally, macro-aggregated albumin scans are performed in few centers, however as this was at the height of the coronavirus pandemic, the scan needed to be performed locally to reduce the chance of the patient getting coronavirus. Local radiographers were remotely instructed on conducting the macro-aggregated albumin scan by a larger center to provide a timely and important investigation in a logistically difficult scenario.
EduRad Publishing
2023-12-20 00:00:00
Peer-reviewed Article, Nuclear Medicine, Molecular Imaging
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https://www.radiologycases.com/index.php/radiologycases/article/view/4411
Journal of Radiology Case Reports; Vol. 17 No. 10 (2023)
eng
Copyright (c) 2023 Journal of Radiology Case Reports
oai:journals.edurad.org:article/4538
2022-06-30T13:03:28Z
radiologycases:NucMed
"220630 2022 eng "
1943-0922
dc
Role of PET imaging in peritoneal involvement of subcutaneous panniculitis-like T-cell lymphoma
Chan, Darren Yak Leong
Singapore General Hospital http://orcid.org/0000-0003-2373-0076
Grigoropoulos, Nicholas Francis
Singapore General Hospital
Tay, Amos Zhi En
Singapore General Hospital
Xie, Wanying
Singapore General Hospital
Subcutaneous panniculitis-like T-cell lymphoma is a rare subtype of cutaneous T-cell lymphomas and represents less than 1% of non-Hodgkin's lymphomas. Currently, the diagnosis is based on clinical and histological findings although clinical features may be nonspecific. Often, it is localised to subcutaneous tissue without lymph node involvement. The literature is sparse but unusual presentations have been described to involve mesentery, breast and even eyelids. Fluorine-18 fluorodeoxyglucose positron-emission tomography/computed tomography has been reported to be useful in assessing disease activity, extent and treatment response in subcutaneous panniculitis-like T-cell lymphoma but we find that it can also be a diagnostic aid for atypical presentations. In our case report, we describe a patient who presented with a neck lump but did not have any other obvious cutaneous lesions. This was biopsied and had histological features in keeping with subcutaneous panniculitis-like T-cell lymphoma. Due to the atypical presentation, positron-emission tomography was crucial for detecting the extracutaneous and likely primary site of disease in the peritoneum, which hence guided the subsequent biopsy to this affected area and confirmed the diagnosis.
EduRad Publishing
2022-06-30 13:03:28
Peer-reviewed Article, Nuclear Medicine, Molecular Imaging
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text/plain
text/plain
https://www.radiologycases.com/index.php/radiologycases/article/view/4538
Journal of Radiology Case Reports; Vol. 16 No. 6 (2022)
eng
Copyright (c) 2022 Journal of Radiology Case Reports