The Teaching Point

Heterotopic ossification can occur in a plethora of clinical settings and sometimes is confused for other entities such as metastatic calcification or osseous/soft-tissue tumors; the distinction can often be made based on the radiographic and clinical course. This case illustrates an unusual occurrence of post-traumatic heterotopic ossification in the setting of an infiltrated intravenous catheter.






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From the manuscript

An Unusual Complication of an Infiltrated Intravenous Catheter: Heterotopic Ossification in a Newborn

Free full text article: An Unusual Complication of an Infiltrated Intravenous Catheter: Heterotopic Ossification in a Newborn

Abstract
Heterotopic ossification refers to formation of lamellar bone in soft tissues. The etiology is diverse and includes genetic, post-traumatic, and metabolic causes. Elicitation of bone morphogenic proteins are thought to play a key role in the pathogenic process. Initially, heterotopic ossification presents a clinical and radiographic challenge in that it can be mistaken for other more worrisome entities which present with calcified soft tissue masses. However, a spontaneous clinical resolution, temporal relationship to an inciting agent, and radiographic evolution to a peripherally-calcified lesion are all clues to the diagnosis. Here we present the clinical and radiographic features of heterotopic ossification as a result of an infiltrated peripheral IV.






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