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Susceptibility weighted imaging may allow for distinguishing between type II ischemia (increased oxygen extraction) from type I ischemia (autoregulatory vasodilatation) in patients with cerebrovascular accident without exposure to ionizing radiation.






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Cerebral Misery Perfusion on Susceptibility Weighted Imaging in Acute Carotid Dissection

Free full text article: Cerebral Misery Perfusion on Susceptibility Weighted Imaging in Acute Carotid Dissection

Abstract
The cerebral vasculature incorporates several fail-safes that must be breached before an irreversible ischemic event takes place. In particular, when autoregulatory vasodilatation fails secondary to falling cerebral perfusion pressure (CPP; stage I hemodynamic failure), increases in the oxygen extraction fraction work to maintain the cerebral metabolic rate of oxygen. Previously, failure of this mechanism, stage II hemodynamic failure, or misery perfusion, has been imaged via positron emission tomography/computed tomography (PET/CT). Current susceptibility-weighted sequences (SWI) allow for more efficient imaging of this physiology. In this case, we identify an incident of reversible ischemia caused by spontaneous carotid artery dissection using a combination of diffusion weighted imaging (DWI) and SWI. The level of hemodynamic failure identified by the imaging sequences elevated the urgency of neurointervention, expediting the patient`s arrival to the neurointerventional table and thus avoiding impending irreversible ischemia.






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Search for articles with similar topics:

Keyword search:

1. cerebral misery perfusion

2. susceptibility-weighted imaging

3. susceptibility weighted imaging

4. SWI

5. carotid artery dissection

6. vertebral artery dissection

7. cerebral autoregulation

8. hemodynamic failure

9. neurointerventional radiology

10. neuroradiology

11. neuroanatomy

12. stroke intervention

13. therapeutic cerebral angioplasty

14. therapeutic cerebral stenting

15. misery perfusion

16. cerebral angiography


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