The Teaching Point

Diffuse proliferative cerebral angiopathy should be considered as a separate entity from "classical" brain AVMs. It is characterized by presence of normal interspersed brain parenchyma, absence of large dominant arterial feeders or nidus and in few cases presence of transdural blood supply. Clinically also it differs from classical AVMs as there is a lesser chance of hemorrhage and the usual presentation is in the form of seizures and headache. Diffuse proliferative cerebral angiopathy is presumably induced as a response to cortical ischemia.






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Diffuse Proliferative Cerebral Angiopathy: A case report and review of the literature

Free full text article: Diffuse Proliferative Cerebral Angiopathy:  A case report and review of the literature

Abstract
Diffuse proliferative cerebral angiopathy is a distinct entity from cerebral arterio-venous malformations; characterized by multiple small arterial feeders and draining veins with normal brain parenchyma seen in-between the abnormal vessels. It is usually seen in younger age group. Here we report a case of diffuse cerebral proliferative angiopathy in a 78-year-old female patient along with discussion of the neuro-imaging findings and review of the literature. It is important to recognize this entity to avoid aggressive surgery or intervention and thus preventing permanent damage to the normal intermingled brain tissue.






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