The Teaching Point

Correct histologic characterization of a suspect breast lesion is important, as diagnostic and therapeutic approach may change significantly. Lymphoma of the breast is rare, but has to be considered in the differential diagnosis when a breast mass is seen. The presented case highlights how PET-CT correctly staged and restaged an oncologic disease, influencing the therapeutic scheme.






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From the manuscript

Rare lymphoid malignancies of the breast: report of two cases illustrating potential diagnostic techniques

Free full text article: Rare lymphoid malignancies of the breast: report of two cases illustrating potential diagnostic techniques

Abstract
Two cases of lymphoid malignancy involving the breast are herein presented. Both patients were admitted with a palpable breast mass. Ultrasound demonstrated hypoechoic, ill-defined lesions of the breast in both patients; mammogram also showed spiculated breast densities. Both patients underwent core biopsy, which revealed lymphomatous cells. Total-body evaluation was also performed by computed tomography and positron emission tomography/computed tomography revealing no other fluorodeoxyglucose-avid foci in the first case and supra and subdiaphragmatic disease in the second one.






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