Question:

Below is an incorrect MRI finding of NOMID:
1. Radiograph shows metaphyseal fraying and cupping.
2. There is heterogenous enhancement at the chondrosseous juntion of the joint.
3. Popliteal lymph node is one of the features.
4. Joint effusion is seen in the majority.
5. There is absence of joint erosion





Answer:

The correct answer for the question "Below is an incorrect MRI finding of NOMID:" is:

4. Joint effusion is seen in the majority.



Explanation
A. Early manifestation of NOMID can mimic ricket such as metaphyseal fraying and cupping.

B. The heterogenous enhancement is due to inflammation and ossification within the physeal mass.

C. This is one of the features seen on MRI review reported by Hill et al.

D. Joint effusion is not usually seen.

E. Absence of joint erosion makes NOMID differentiable from juvenile rheumatoid arthritis.



From the manuscript:
NOMID: The radiographic and MRI features and review of literature
Radiology Case. 2012 Mar; 6(3):1-8


This article belongs to the MSK section.




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From the manuscript

NOMID: The radiographic and MRI features and review of literature

Free full text article: NOMID: The radiographic and MRI features and review of literature

Abstract
Neonatal onset multisystem inflammatory disease (NOMID) is a rare autoinflammatory disorder, which manifests early in infancy. We describe a case of a 10-year-old boy who has been unwell since infancy. He presented with urticarial rash, intermittent fever and hepatosplenomegaly followed by progressive arthropathy. His joint symptoms started at two years of age, which progressively involved multiple joints, resulting in bone and joint deformities. A series of joint radiographs demonstrated bizarre enlarging physeal mass with heterogenous calcification. Magnetic resonance imaging (MRI) of the involved right ankle and knee showed characteristic thickened and calcified physeal lesions, which enhanced post-gadolinium. This debilitating disease is also known to involve the central nervous system and eyes. This case report aims to highlight the conventional radiographic and magnetic resonance imaging (MRI) findings of this physeal abnormality in NOMID syndrome.






References



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