Question:

Kikuchi Fujimoto disease:
1. typically presents with uveitis
2. is commonly seen in Hispanic males
3. is secondary to bacterial infection
4. usually presents with lymphadenopathy and fever
5. none of the above





Answer:

The correct answer for the question "Kikuchi Fujimoto disease:" is:

4. usually presents with lymphadenopathy and fever



Explanation

(Kikuchi-Fujimoto disease (KFD), also called histiocytic necrotizing lymphadenitis, is an uncommon, idiopathic, usually self-limited cause of lymphadenitis and fever.

a) incorrect: (It has also been associated with systemic lupus erythematosus, arthritis, and rarely uveitis.)

b) incorrect: (Women are affected more than men (although the female preponderance appears now to be less than originally thought) and, to date, most cases that have been reported are from East Asia.)

c) incorrect: (KFD has been reported in association with many infectious disease processes including cytomegalovirus, Epstein-Barr virus, human herpes virus, varicella-zoster virus, and parvovirus B19.)



From the manuscript:
Kikuchi-Fujimoto Disease with Bilateral Uveitis
Radiology Case. 2009 Jul; 3(7):1-6


This article belongs to the Neuro section.




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From the manuscript

Kikuchi-Fujimoto Disease with Bilateral Uveitis

Free full text article: Kikuchi-Fujimoto Disease with Bilateral Uveitis

Abstract
Kikuchi-Fujimoto disease (KFD), also called histiocytic necrotizing lymphadenitis, is rare condition that usually presents with lymphadenitis and fever. KFD has been associated with many infectious disease processes, predominantly viral. Association with systemic inflammatory processes has been described. Here we present a case of KFD with the rare ocular manifestation of bilateral anterior uveitis, and corresponding findings on magnetic resonance imaging (MRI).






References



1. Bosch X, Guilabert A. Kikuchi-Fujimoto disease. Orphanet Journal of Rare Diseases 2006; 1:18
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2. Bosch X, Guilabert A, Miquel R, Campo E. Enigmatic Kikuchi-Fujimoto disease: a comprehensive review. Am J Clin Pathol 2004; 122:141-152
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3. Hamdan AL, Jaber M, Tarazi A, Tawil A, Fuleihan N. Kikuchi Fujimoto disease: case report and review of the literature. Scand J Infect Dis 2002; 34(1): 69-71
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4. Kim S.H., Kim S.K., Chung H, Lee H.S., Kim H.B., Park K.H. Bilateral Anterior Uveitis as an Unusual Manifestation of Kikuchi Fujimoto Disease. Rheumatology (oxford), August 2004; 43(8)
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5. Mafee M, Linder B, Peyman G, Langer B, Choi K, Capek V. Choroidal hematoma and effusion: evaluation with MR imaging. Radiology 1988; 168:781-786
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6. Mafee M, Peyman G. Choroidal detatchment and ocular hypotony: CT evaluation. Radiology 1984; 153: 697-703
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This article belongs to the Neuro section.


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