Question:

Standard treatment for solitary fibrous tumors consists of which of the following?
1. Surgical resection with clear margins alone
2. Chemotherapy alone
3. Radiation alone
4. Surgical resection followed by adjuvant chemotherapy
5. Surgical resection followed by radiation therapy





Answer:

The correct answer for the question "Standard treatment for solitary fibrous tumors consists of which of the following?" is:

1. Surgical resection with clear margins alone



Explanation
1.  Surgical resection is the treatment of choice for SFTs and in most cases is definitive treatment. [Resection with clear margins yields the best chance for curing SFTs with or without malignant features.]

2.  SFTs have had disappointing results with classical chemotherapy. [Adjuvant chemotherapy is rarely successful, and SFTs are regarded as chemoresistant.]

3. Radiation alone is not recommended unless the patient cannot tolerate surgery.

4. SFTs are not typically treated with adjuvant chemotherapy. Some newer chemotherapies are being investigated, including tyrosine kinase inhibitors.

5. Standard treatment consists of surgical resection alone. For some cases of aggressive disease, radiation therapy is used as an adjunct to surgery. [Radiotherapy can be considered if tumor displays evident criteria for malignancy or if the surgical margins were positive.]



From the manuscript:
Solitary Fibrous Tumor of the Infratemporal Fossa
Radiology Case. 2014 Dec; 8(12):1-8


This article belongs to the Neuro section.




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From the manuscript

Solitary Fibrous Tumor of the Infratemporal Fossa

Free full text article: Solitary Fibrous Tumor of the Infratemporal Fossa

Abstract
Solitary fibrous tumors represent fewer than 2% of all soft tissue tumors, and only about 12-15% of them occur in the head and neck. We report a case of a 38-year-old male who presented with a six-month history of increasing right cheek swelling. Computed tomography of the paranasal sinuses with contrast demonstrated a well-circumscribed avidly enhancing mass in the right retroantral fat. On magnetic resonance imaging the lesion was homogenously slightly hyperintense to muscle on T1 weighted and T2 weighted images and enhanced avidly with contrast. Surgical resection was performed and pathology was consistent with solitary fibrous tumor. There have been very few reported cases of solitary fibrous tumors in the infratemporal fossa and none described as originating in the retroantral fat.






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1. Solitary fibrous tumor

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