Question:

What are true statements about leiomyoma in uterus?
1. It is most common solid pelvic tumour in women.
2. It arises from endometrium.
3. Most patients are symptomatic.
4. It is estrogen-dependent tumour.
5. It grows in size in menopause.





Answer:

The correct answers for the question "What are true statements about leiomyoma in uterus?" are:

1. It is most common solid pelvic tumour in women.

4. It is estrogen-dependent tumour.



Explanation
1. It is most common solid pelvic tumour in women. [It occurs in 20-40% of women during their reproductive years.]

2. It arises from smooth muscle cells of uterus. [It is a benign tumour of uterus arising from smooth muscle cells of uterus. It can be subserosal, intramural or submucosal in the uterus.]

3. Most patients are asymptomatic. [Most patints are asymptomatic but when symptoms occur they depend upon location and size of tumour. Most common symptom is menstrual bleeding.]

4. It is dependent upon estrogen level. [Its growth is estrogen dependent. It shows maximum growth during reproductive years of women because during that period estrogen level is maximum.]

5. It decreases in size during menopause. [It decreases in size in menopause due to low level of estrogen.]



From the manuscript:
Large leiomyoma in a woman with Mayer-Rokitansky-Kuster-Hauser syndrome
Radiology Case. 2013 Mar; 7(3):39-46


This article belongs to the OB/GYN section.




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From the manuscript

Large leiomyoma in a woman with Mayer-Rokitansky-Kuster-Hauser syndrome

Free full text article: Large leiomyoma in a woman with Mayer-Rokitansky-Kuster-Hauser syndrome

Abstract
Mayer-Rokitansky-Kuster-Hauser (MRKH) syndrome is a rare congenital anomaly characterized as aplasia or hypoplasia of uterus and vagina in women with normal development of secondary sex characteristics. It affects 1 in 4000-5000 female births. Women with this syndrome present with primary amenorrhoea. MRKH syndrome may be associated with renal, skeletal, cardiac and auditory anomalies. Women with MRKH syndrome may develop leiomyoma from a rudimentary uterus, though very rare. Initial investigation in women having MRKH syndrome with leiomyoma is ultrasonography (USG). However, CT and MRI are more accurate to evaluate the pelvic anatomy and pathologies.






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