Question:

With regards to primary breast lymphoma:
1. Primary breast lymphoma may present as a breast mass or as a diffuse infiltrative process.
2. Prognosis is better in younger patients with primary breast lymphoma.
3. A 5 year survival can be calculated using the International Prognostic Index.
4. Surgery is required to remove tumour bulk in primary breast lymphoma.
5. Primary breast lymphoma treatment includes chemotherapy and radiation therapy.





Answer:

The correct answers for the question "With regards to primary breast lymphoma:" are:

1. Primary breast lymphoma may present as a breast mass or as a diffuse infiltrative process.

3. A 5 year survival can be calculated using the International Prognostic Index.

5. Primary breast lymphoma treatment includes chemotherapy and radiation therapy.



Explanation
1. Applies [Two groups are noted on imaging. They are well circumscribed masses (solitary or multiple) or a diffuse infiltrative type].

2. Prognosis is worse in younger patients. [Poor prognostic factors include a younger age, tumour size > 5cm, synchronous bilateral disease and axillary nodal involvement].

3. Applies. [The International Prognostic Index predicts 5 year survival based on age, LDH level, staging, extranodal disease, performance status].

4. Surgery is no longer indicated [Primary breast lymphoma is not a surgical disease and can be treated successfully with combined chemotherapy and radiation therapy].

5. Applies [There is no general agreement on the appropriate treatment of primary breast lymphoma. Recent articles recommend chemotherapy for bulky or stage II disease. Chemotherapy regimes vary with histologic subtype. Radiation therapy can be used to provide effective local control or may be adjuvant to chemotherapy].



From the manuscript:
Primary Breast Lymphoma: A Rare Entity
Radiology Case. 2011 May; 5(5):1-9


This article belongs to the Mamms section.




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From the manuscript

Primary Breast Lymphoma: A Rare Entity

Free full text article: Primary Breast Lymphoma: A Rare Entity

Abstract
In the past two decades there has been an increase in the incidence of Non-Hodgkin Lymphoma and Hodgkin disease. This has been accompanied by an increase in the numbers of extranodal lymphoma. Despite this primary breast lymphoma is a rare disease. We present a case of a 74 year old female with primary breast lymphoma. Methods of imaging including PET/CT are discussed. Criteria for diagnosing primary breast lymphoma are presented. In addition diagnostic methods and therapeutic options are considered.






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