Question:

Which tracer is preferable in simultaneous assessment of differential function and renal transit?
1. Renal scan with 99mTc- Dimercaptosuccinic acid (DMSA).
2. 99mTc diethylenetriamine pentaacetic acid (DTPA).
3. 99mTc mercaptoacetyltriglycine (MAG3).
4. I-131-orthoiodohippurate (I-131-OIH).
5. 99mTc Glucoheptonate (GHA).





Answer:

The correct answer for the question "Which tracer is preferable in simultaneous assessment of differential function and renal transit?" is:

3. 99mTc mercaptoacetyltriglycine (MAG3).



Explanation
[Because of its ready availability and excellent imaging characteristics MAG3 is considered as favored agent for dynamic renography.]



From the manuscript:
Impact of geometric mean imaging in the accurate determination of partial function in MAG3 renal scanning in a patient with retroperitoneal mass
Radiology Case. 2011 June; 5(6):9-17


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From the manuscript

Impact of geometric mean imaging in the accurate determination of partial function in MAG3 renal scanning in a patient with retroperitoneal mass

Free full text article: Impact of geometric mean imaging in the accurate determination of partial function in MAG3 renal scanning in a patient with retroperitoneal mass

Abstract
Liposarcoma frequently occurs in the retroperitoneum and lower extremities, accounting for 20% of all mesenchymal malignancies. Liposarcomas vary by histology and can be classified into four types. Those four types are well differentiated, myxoid/round cell, pleomorphic and dedifferentiated. Due to retroperitoneal location of this tumor, it is expected to affect the kidney position. Renography has provided a unique tool for noninvasive evaluation of various functional parameters e.g. relative renal function. Most renography studies are carried out using the posterior view, under the assumption that the depths of both kidneys are similar so that the radiotracer counts in the region of interest will be attenuated to the same extent. Errors in estimation of the relative renal function may arise if the kidneys are at different depths e.g. secondary to a pushing tumor. Geometric mean imaging from combined anterior and posterior views helps to overcome this issue. This case shows the impact of geometric mean imaging in the truthful determination of partial function in patients with retroperitoneal liposarcoma.






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